Detection circuit design and fabrication for low-field RASER-NMR

Research topic/area

NMR, Maschinenbau, Elektrotechnik, Physik, Ingenieurwesen

Type of thesis

Bachelor / Master

Start time

30.11.2024

Application deadline

31.03.2025

Duration of the thesis

6-9 months

Description

Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique that uses the magnetic properties of selected atomic nuclei (i.e. 1H, 13C, 15N, 19F) to investigate molecular structures and the dynamics of processes. The detection signal can be amplified up to sub-millihertz range with RASER (Radio-frequency Amplification by Stimulated Emission of Radiation), which is an innovative technique in magnetic resonance. RASER operational principles are similar to a laser, but in the radio-frequency domain, where it creates a population inversion in nuclear spins, typically using para-hydrogen as a pumping mechanism, and coupling it with a high-Q resonator to achieve stimulated emission of radio waves.

In our research group in the Institute for Microstructure Technology (IMT), we focus on the on the developing of the novel approach for NMR-RASER at low magnetic field (1µT - 10mT), which allows hyperpolarisation of atomic nuclei directly within the developed electromagnet system. The low magnetic field can be also utilized in specialized MRI imaging using extended hardware.

This project will involve tasks including:
• Resonator design for detection of various nuclei, e.g. 1H, 13C or 15N;
• Resonator assembly and system integration;
• Design and fabrication of components with machining or additive manufacturing;
• NMR spectroscopy with RASER and MRI at low magnetic field.

You will be part of a larger team within the Institute of Microstructure Technology (IMT), which offers you the possibility to fabricate and test the processes and devices and gives you the opportunity to co-author conference and/or journal publications.

Requirement

Requirements for students

• Good academic record;
• Fluent English and/or German, good communication and presentation skills;
• Knowledge/experience in electronics and/or mechatronics;
• Interest in electronics and electro-mechanics applied in the intersection of chemistry and biology;
• Candidate should reside in Germany/EU;
• Self-motivation to work as a team member and independently;
• Enthusiasm to work in multidisciplinary, multicultural environment.

Faculty departments

• Engineering sciences
  Electrical engineering & information technologies
  Mechatronics & information technologies
• Natural sciences and Technology
  Physics

Supervision

Title, first name, last name

Dr. Emil Mamleyev; Dr. Sören Lehmkuhl

Organizational unit

Institute of Microstructure Technology

Email address

emil.mamleyev@kit.edu

Link to personal homepage/personal page

Website

Application via email

Application documents

• Cover letter
• Curriculum vitae
• Grade transcript
• Certificate of enrollment

E-Mail Address for application
Senden Sie die oben genannten Bewerbungsunterlagen bitte per Mail an emil.mamleyev@kit.edu


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